Health Benefits of Pantethine and Recommendation Intake

√ Scientific Checked Pass quality checked by advisor, read our quality control guidelance for more info

Pantethine is a derivative of active compound from vitamin B5 or otherwise known as pantothenic acid, with the addition of cysteamine.

They are used for lowering cholesterol, preventing inflammation, accelerating the immune system’s activities, treatment of gastrointestinal (GI) diseases, cystinosis and finally for boosting physical performance.

At the same time, it also increases energy, lowers the risk of both cardiac arrests plus stroke, prevents mental, physical as well as psychological stress, improves the adrenal function, up to protecting against allergic reactions to those who are allergic to formaldehyde. Now, we will talk more about pantethine itself, as well as the health benefits of pantethine.

How does it Work?

Pantethine may increase the concentrations of chemicals that reduce triglycerides as well as blood cholesterol. It is needed for situations that require coenzyme A, such as in fat or carbohydrate processing. Other than that, pantethine helps mitochondria or the cells’ mini energy producers, by turning lipids into energy to enhance energy production in every cell inside the body. On the other hand, during stresses it also supports a healthy function of the adrenal cortex plus hormone synthesis.

Nonetheless, pantothenic acid remains a vital asset to our everyday bodily functions, because lack of it may result in simple problems such as fatigue and sleeping issues.

What are its Health Benefits?

  1. Pantethine is a Source of Anti Inflammatory

The adrenal glands require coenzyme A (CoA) as well as pantothenic acid to produce cortisol, which is an important type of anti-inflammatory substance found inside the body. In the meantime, it also supports the immune system while aiding in all fats, carbohydrate metabolism as well as protein. Besides, several animal experiments concluded that a lack of vitamin B5 may affect the adrenal cortex’s functions.

  1. Pantethine Aids Metabolism and is Important for Basic Bodily Functions

Red blood cells heavily need pantothenic acid in order for it to be produced, and so are hormones such as those that produce steroid or sexual hormones. In terms of digestion, pantethine is important for the maintenance of a healthy digestive tract, the synthesis of essential lipids, as well as neurotransmitters. This has made the pantethine to be essential for the metabolism process that involves lipids as well as carbohydrates.

  1. Pantethine Helps to Reduce Physical and Psychological Stress

Both human and animal results observed that pantothenic acid may allow human beings to sustain adaptive response and also minimize the health risks of stress and symptoms of depression that are deemed as systemic. This is also possible thanks to the increased release of corticosterone that responds to many forms of stress. Corticosterone itself is made using adrenal glands that needs pantothenic acid to boost the production of CoA.

  1. Pantethine Supports Cardiovascular Health

Pantethine supports cardiovascular health in terms of converting both fats and carbohydrates into health benefits of glucose. D-Pantothenic acid helps to balance and lower cholesterol levels while lowering hypertension and therefore lowering risks of heart attacks.

  1. Pantethine is Also Essential for Liver Function

The liver is made up of high reserves of CoA or coenzyme A. In fact, pantothenic acid itself makes up CoA. High CoA values help the body to protect itself and get rid of the foreign substances one is exposed to, hence allowing the liver to function at a maximum.

  1. Pantethine Prevents Hair Loss

It is said that pantethine is more effective than placebo when it comes to improving hair quality and also preventing the possibilities of hair loss. In another study, pantethine when combined with caffeine, niacinamide, dimethicone as well as acrylate polymer significantly increased the diameter of hair fibres while increasing suppleness and also strength.

  1. Pantethine Treats Respiratory Problems

A previous test involving a 5-year old boy with 2-years of suffering symptoms of asthma resulted in a remarkable improvement and prevention of recurring asthmatic attacks. In the meantime, a separate middle-aged symptoms of flu patient who was orally given vitamin B5 had his cold stopped immediately 10 minutes after treatment. This goes to show that pantethine’s is indeed effective in treating both light and serious respiratory problems.

  1. Pantethine Soothes and Reduces Pain in the Eyes

Unknown to majority, however the fact remains that eye drops use vitamin B5 or pantothenic acid, which comes in the form of dexpanthenol. Dexpanthenol is also a common ingredient present in dermatological ointments that help to reduce pain and inflammation caused by dry eyes.

  1. Pantethine May also Make the Skin Healthy

Pantethine helps the skin to look healthy and young thanks to the moisturizing effects it provides. A moist skin is also an indicator that the skin is well hydrated. In the meantime, pantothenic acid deficiency also leads to acne. On the other hand, calcium pantothenate speeds up wound healing process by repairing the skin, such as in post surgeries. 

Dosage When Taking Pantethine

If one would like to treat excess fat inside the blood (hyperpoproteinemia), please consume 300 mg of pantethine pills from 3 up to 4 times daily. This is the complete list of daily pantethine dosage for people across various age ranges;

  • 7 mg for infants under six months of age
  • 8 mg for infants aged 6 to 12 months
  • 2 mg for children aged 1 to 3 years
  • 3 mg for children aged 4 to 8 years
  • 4 mg for children aged 9 to 13 years
  • 5 mg for anyone 14 years or older
  • 6 mg for pregnant women
  • 7 mg for breastfeeding mothers

Side Effects of Pantethine

Routine oral consumption of pantethine is most likely to be safe for a year’s time. However, pantethine may trigger nausea, stomach discomfort, as well as diarrhea.

For those who suffer from bleeding disorders, there have been evidences wherein pantethine slows down blood clotting, thus several healthcare experts worry that pantethine could further cause severe bleeding in patients of this condition. Thus, for those with bleeding disorders, it is best to seek medical advice at first. In relation to this, it is wise for one to also stop using pantethine at least 2 weeks prior to if someone is scheduled for surgery.